![]() ![]() Together with obesity, KOA is believed to affect mostly Americans aged 50–84 years. Its main signs and symptoms include arthralgia, ankylosis, and functional disorders. It is associated with many factors such as age, body mass index, sex, inflammation, long-term improper exercise, and heredity. Knee osteoarthritis (KOA) is a common chronic progressive disease characterized by the degeneration and secondary bone hyperplasia of the knee articular cartilage. Trial registrationĬhiCTR, ChiCTR-INR-16008032. The results of the trial will compare the efficacy on KOA between crossbow needle group and acupuncture group and will be expected to make a systematic and objective evaluation of crossbow needle therapy. The secondary outcomes will include Lysholm knee score, Japanese Orthopedic Association (JOA) knee score, visual analogue scale (VAS), and the MOS 36-item short-form health survey (SF-36). The primary outcome will be the Western Ontario and McMaster Osteoarthritis Index (WOMAC) score at baseline, the end of treatment, first follow-up, and second follow-up. Follow-up will be conducted 15 days and 30 days after treatment. Patients in each group will receive treatment every other day, three times a week, 20 times in total. Three hundred and six patients will be randomly assigned to a crossbow needle group ( n = 153) and an acupuncture group ( n = 153). The trial is a randomized, multicenter, parallel, non-inferiority study. Studies of small sample size have seen significant improvement on pain relief, stiffness, and joint function. Crossbow needle therapy of the Miao ethnic minority group is intended for KOA treatment and has been widely used. Therefore, treatment of KOA is mainly focused on relieving pain, reducing inflammation, improving or restoring joint function, delaying disease progression, and increasing quality of life. ![]() It is characterized by the degeneration and secondary bone hyperplasia of the articular cartilage the pathologic changes are irreversible. Knee osteoarthritis (KOA) is commonly seen and has a high occurrence in the middle-aged and elderly. ![]()
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